Roland G. Huber studied Chemistry at the University of Innsbruck and wrote his master and PhD thesis in the laboratory of Prof. Klaus R. Liedl on entropy and biomolecular dynamics in ligand binding. He was awarded a DOC fellowship by the Austrian Academy of Sciences, which allowed him to complete parts of his study at the laboratory of Prof. William L. Jorgensen at Yale University. After completing his PhD, he joined the group of Peter J. Bond at BII, A*STAR Singapore in 2014. In 2016, Roland G. Huber was awarded a Young Investigator Grant by the Biomedical Research Council (BMRC), A*STAR to conduct research on the interactions of viral proteins with viral genomic RNA in collaboration with researchers from GIS, A*STAR and Duke-NUS medical school, and hosted collaborators through an EMBO short-term fellowship. In 2019 he was appointed as Assistant Principal Investigator at BII, A*STAR.
Roland G. Huber’s research focuses on the structure and function of RNA. The key focus in on integrating sequence, structural, and computational methods to elucidate key functional regions of viral and human RNA. RNA adopts a wide diversity of structure, but at the same time exhibits a high degree of flexibility and a plurality of interactions. This makes functional RNA structures challenging to approach with classical biomolecular structure elucidation techniques alone, and calls for new integrative data analysis approaches.
|Senior Post-Doctoral Research Fellow|| DEFALCO Louis |