BioMedical Data Architecture & Repository

Research

BioMed DAR is a SSSO (Standard Systems Support Office) to provide clinical research data management support to strategic (past, current, future) A*STAR BMRC programmes; Briefly, DAR manages the data life cycle of the cohort datasets through 3 operatives - data governance, data management operations (cleaning, integration, cataloguing, movement, usage) and s/w development. DAR builds and uses its own in-house data warehouse, data catalogue, data visualizers and secured data exchange API libraries. In-house s/w builds allow us to adapt and integrate data management or governance workflow into our systems easily. Currently, DAR helps to host IAF programs like ATTRaCT, CaLiBre, WCIT and GUSTO. 

On data security, it is important to note that DAR does not store identifiable datasets and works with clinical data stakeholders to import only de-identified data into BII. Meanwhile, DAR operates within the BII ISO27001 certified environment for hosting its data warehousing, ETL processes and data sandboxes where strict SOP are in place to track data movement. Physically, the ISO27001 servers are located in designated server rooms where staff movement are logged and captured through CCTV. As an additional measure, the ISO27001 servers are caged up to pose further deterrence to the physical access of the disk drives.

On data governance, data access of each cohort dataset needs to be approved by the respective cohort’s DAC (data access committee). This requires the project proposal to clearly define the purpose, scope and duration of the data usage and then subjected to a DAC review. Only upon DAC approval, the scoped dataset will then be ETLed (extract/transform/load) from DAR’s data warehouse to a designated VPN sandbox environment for its intended usage. Generally, no export of data will be allowed while the analysis results will need further approval by a data concierge team.

Members

 Principal Investigator WONG Wing Cheong     
 Assistant Principal Investigator TAN Ming Zhen
 Software Engineering Manager TAY Wei Hong 
 Project Manager FUN Max
 Full Stack Software Developer LIM Aloysius
 Software Developer HO Wei Chin
 Software Developer KOH Ziying

 

Methodology/Software Publications